Extracellular matrix expansion by cardiac magnetic resonance T1 mapping- validation with myocardial biopsy

نویسندگان

  • Andreas Kammerlander
  • Caroline Tufaro
  • Alina F Bachmann
  • Beatrice A Marzluf
  • Stefan Aschauer
  • Andreas Greiser
  • Diana Bonderman
  • Julia Mascherbauer
چکیده

Background Accumulation of diffuse myocardial fibrosis / extracellular volume (ECV) in the myocardium is common to various cardiac diseases and is associated with an unfavorable prognosis. Various cardiac magnetic resonance (CMR) T1 mapping techniques have recently been proposed for the quantification of ECV, including: 1. Modified Look-Locker Inversion recovery (MOLLI) T1 mapping including calculation of ECV, 2. Post-contrast multiple-breath-hold T1 mapping. 3. Native (precontrast) T1 mapping. T1 mapping is a promising technique, however, validation data based on myocardial biopsy are sparse.

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عنوان ژورنال:

دوره 17  شماره 

صفحات  -

تاریخ انتشار 2015